Post by fb on Sept 16, 2020 22:18:03 GMT
Vaccin är inte det enda sättet varmed corona kan bekämpas, förhindras eller stoppas. Men de alternativ som finns, kan komma att finnas, utvecklas eller kanske kan tänkas utvecklas hamnar utanför den politiska prioriteringen. Eftersom marknaden inte är fri så kan vi gå miste om dessa möjligheter. De handlar om att antingen kurirera covid-19-patienter medicinskt eller att förhindra sjukdomen på annat sätt än med klassisk vaccination.
We just might have a cure before we get to a vaccine. And it is small enough to be made in peptide factories.
If we were free, the peptide makers would be ordering ingredients and re-configuring factories. Hospital trials would start within the week.
What we have, instead, is federal agencies totally invested in vaccines. My fear is that we will see a massive and long-term assertion of government power to save us from the cure. Abroad, we may see manufacturing and hospital trials soon. I would book a ticket now, if I knew to where.."
If we were free, the peptide makers would be ordering ingredients and re-configuring factories. Hospital trials would start within the week.
What we have, instead, is federal agencies totally invested in vaccines. My fear is that we will see a massive and long-term assertion of government power to save us from the cure. Abroad, we may see manufacturing and hospital trials soon. I would book a ticket now, if I knew to where.."
The article, "High potency of a bivalent human VH domain in SARS-CoV-2 animal models," is here:
Authors: Wei Li, Alexandra Schäfer, Swarali S. Kulkarni, Xianglei Liu, David R. Martinez, Chuan Chen, Zehua Sun, Sarah R. Leist, Aleksandra Drelich, Liyong Zhang, Marcin L. Ura, Alison Berezuk, Sagar Chittori, Karoline Leopold, Dhiraj Mannar, Shanti S. Srivastava, Xing Zhu, Eric C. Peterson, Chien-Te Tseng, John W. Mellors, Darryl Falzarano, Sriram Subramaniam, Ralph S. Baric, Dimiter S. Dimitrov.
Scientists at the University of Pittsburgh School of Medicine have isolated a tiny molecule, Ab8, that may prevent and cure a COVID-19 infection (link).
Ab8 not only has potential as therapy for COVID-19, but it also could be used to keep people from getting SARS-CoV-2 infections," said co-author John Mellors, chief of the Division of Infectious Diseases at Pitt and UPMC. "Antibodies of larger size have worked against other infectious diseases and have been well tolerated, giving us hope that it could be an effective treatment for patients with COVID-19 and for protection of those who have never had the infection and are not immune.
Researchers are "thinking outside the box" for how the drug could be administered, stating it may be able to be inhaled or through a superficial injection, instead of an IV.
According to the report, the team at University of Texas Medical Branch Center for Biodefense and Emerging Diseases and Galveston National Laboratory tested Ab8 and found it blocked the virus from entering cells. In mice trials, those treated with Ab8 had 10-fold less of the amount of infectious virus compared to those that were untreated.
Ab8 not only has potential as therapy for COVID-19, but it also could be used to keep people from getting SARS-CoV-2 infections," said co-author John Mellors, chief of the Division of Infectious Diseases at Pitt and UPMC. "Antibodies of larger size have worked against other infectious diseases and have been well tolerated, giving us hope that it could be an effective treatment for patients with COVID-19 and for protection of those who have never had the infection and are not immune.
Researchers are "thinking outside the box" for how the drug could be administered, stating it may be able to be inhaled or through a superficial injection, instead of an IV.
According to the report, the team at University of Texas Medical Branch Center for Biodefense and Emerging Diseases and Galveston National Laboratory tested Ab8 and found it blocked the virus from entering cells. In mice trials, those treated with Ab8 had 10-fold less of the amount of infectious virus compared to those that were untreated.